| | Statistic | FOR | OPP |
| Total Yards per Game | 352.5 | 413.5 |
| Rushing YDS per ATT | 4.6 | 5.0 |
| Passing YDS per ATT | 7.0 | 7.0 |
| Passing Comp % | 0.638 | 0.756 |
| Total YDS per Play | 6.0 | 6.3 |
| Total YDS per Point | 16.8 | 14.5 |
|
| Injury |
| [G] 09/21/2021 - Nick Gates IR ( Leg ) |
| [LB] 09/15/2021 - Cam Brown is "?" Sunday vs Atlanta ( Hamstring ) |
| [OL] 09/15/2021 - Shane Lemieux is "?" Sunday vs Atlanta ( Knee ) |
| [TE] 09/13/2021 - Evan Engram is "?" Sunday vs Atlanta ( Calf ) |
| [LB] 09/06/2021 - T.J. Brunson IR ( Knee ) |
| [TE] 09/06/2021 - Rysen John IR ( Ankle ) |
| [WR] 09/06/2021 - Austin Mack IR ( Hamstring ) |
| [OL] 09/06/2021 - Kyle Murphy IR ( Ankle ) |
| [DB] 09/06/2021 - Joshua Kalu IR ( Pectoral ) |
| [WR] 09/06/2021 - John Ross III IR ( Hamstring ) |
| [LB] 09/06/2021 - Elerson Smith IR ( Hamstring ) |
| [CB] 09/06/2021 - Quincy Wilson IR ( Ankle ) |
| [LB] 08/28/2021 - Ryan Anderson 6 week suspension eligible to return 10/24 vs Carolina ( Suspension ) |
| [TE] 08/09/2021 - Levine Toilolo IR ( Achilles ) |
